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SEPT 09, 2025

The Essential Do’s and Don’ts of Taking Supplements


Make supplements work for you with simple do’s and don’ts: when to take them, how to swallow them, and how to stay organized without risking your health.

Read time: 10 minutes

Everyone loves a good daily supplement. Walk into any pharmacy, grocery store, or even a gas station, and you’ll see shelves lined with bottles promising more energy, better sleep, stronger hair, and sharper focus. For many people, supplements are an everyday part of their health routine, whether that’s a simple multivitamin or a carefully curated lineup of powders, capsules, and tablets.

But just buying supplements and swallowing them whenever you remember isn’t enough. The way you actually take them - how you swallow them, when you take them, what you take them with, and how you stay organized - can make the difference between actually benefiting from them or just wasting your money.

And if you’ve ever choked on a giant fish oil capsule, felt queasy after a morning vitamin, or completely lost track of whether you already took your magnesium dose that day, you’re not alone. The good news is that a handful of practical do’s and don’ts can make supplement-taking easier, safer, and far more effective.

✅ Do: Learn How to Swallow Pills Without Struggle

One of the biggest challenges people face with supplements isn’t remembering to take them, it’s getting them down in the first place. Capsules and tablets can be surprisingly tricky, especially the oversized ones like omega-3s, collagen, or calcium.

Here’s a simple hack most people don’t know: instead of tilting your head back, try leaning your head forward slightly as you swallow. This changes the angle of your throat, making it easier for the pill to slide down.

Why does this work? Capsules are designed to float, and when you tilt your head back, they can bob around at the top of your throat, making swallowing harder. Tilting forward encourages the pill to move with the flow of water.

And another golden rule: only take one pill per mouthful. It’s tempting to try and swallow two or three at a time, but that’s asking for trouble. Pills can stack awkwardly, get stuck, or trigger gagging. Taking them one by one only takes an extra few seconds but makes the process smoother and safer.

If you still struggle, you can try:

  • Taking capsules with thicker liquids like a smoothie or yogurt, which can “carry” them down.
  • Using a pill-swallowing cup or gel coating products that help pills glide more easily.
  • Asking your pharmacist if a liquid or chewable version is available.

Don’t let the swallowing part be the thing that makes you avoid supplements altogether, there are workarounds.

❌ Don’t: Take Supplements on an Empty Stomach

This is one of the most common mistakes people make. Popping vitamins first thing in the morning before breakfast might seem efficient, but it can leave you with nausea, stomach cramps, or just wasted nutrients that your body doesn’t absorb properly.

Here’s why:

  • Fat-soluble vitamins (A, D, E, and K) need dietary fat to be absorbed effectively. Without it, you may only get a fraction of the benefit.
  • Minerals like iron or zinc can be harsh on the stomach, causing discomfort or even nausea if you take them without food.
  • Even water-soluble vitamins like vitamin C can cause irritation or acid reflux if taken on an empty stomach.

The solution is simple: pair your supplements with food. It doesn’t need to be a big, heavy meal, something as light as a slice of whole grain toast with nut butter or a bowl of yogurt can do the trick.

Think of supplements as something that should complement your meals, not replace them. Which leads us to the next point.

❌ Don’t: Use Supplements as a Meal Replacement

It’s easy to fall into the trap of thinking, “Well, I take a multivitamin, so I don’t need to worry as much about what I eat.” But supplements were never designed to replace whole foods.

Food contains a complex mix of vitamins, minerals, fiber, and phytonutrients that simply can’t be replicated in a capsule. For example:

  • An orange doesn’t just give you vitamin C, it delivers flavonoids and antioxidants that help your body use that vitamin C more effectively.
  • Leafy greens don’t just supply folate, they also contain fiber, magnesium, and dozens of plant compounds that support health in ways supplements can’t.

When you rely solely on pills, you miss out on the synergy of nutrients working together. Supplements should be your “backup plan,” not your main strategy.

So enjoy real meals made with whole, colorful foods, and let supplements step in to cover the small gaps.

✅ Do: Keep Yourself Organized

Here’s something most people underestimate: consistency is the real key to getting results with supplements. Taking your vitamin D once a week when you remember won’t give you the same benefits as taking it daily. But staying on track can be surprisingly hard when you’re juggling multiple bottles.

This is where a pill organizer is your best friend. Instead of opening five different bottles every morning, you can prep your doses for the week in advance.

The ultimate standout option is the PROMIXX Core pill organizer. It’s not your typical clunky, plastic box. It has:

  • Clear compartments so you can see exactly what you’ve already taken (no second-guessing).
  • A secure lock lid to prevent spills when you toss it in your bag.
  • Magnetic stackability, which means you can easily expand your organizer as your routine changes.

It’s the investment that pays off in peace of mind and keeps your supplement routine stress-free.

✅ Do: Respect Dosages and Listen to Your Body

Another important point: more is not always better when it comes to supplements.

It’s easy to think doubling up on vitamins will give you double the benefits, but in reality it can cause side effects or even harm. For example:

  • Too much iron can lead to toxicity and damage organs.
  • Excess vitamin D can cause dangerously high calcium levels in the blood.
  • Mega-doses of vitamin C may just give you digestive issues without any added benefit.

That’s why it’s smart to:

  • Follow the dosage instructions on the label.
  • Talk to your doctor before starting something new, especially if you’re on prescription medication.
  • Pay attention to how your body responds. If something makes you feel off, stop and reassess.

Remember, supplements are meant to support health, not push your body into extremes.

✅ Do: Build Supplements Into Your Lifestyle

The best supplement routine is one you don’t have to think too hard about. Here are a few tips to make it seamless:

  • Pair supplements with daily habits. For example, keep your PROMIXX Core pill organizer next to your toothbrush or coffee maker so you remember to take them at the same time every day.
  • Set reminders. A quick phone alarm or calendar notification can save you from missed doses.
  • Travel smart. Keep a small organizer in your bag so you’re not carrying five bulky bottles everywhere.

Making supplements part of your natural flow is far more effective than relying on willpower alone.

The Bottom Line

Taking supplements doesn’t need to be complicated, but it does require a little thought and consistency. By following these simple do’s and don’ts, you’ll get the most out of your investment in health:

✅ Lean forward to make swallowing easier.

✅ Take one pill at a time.

❌ Don’t take them on an empty stomach.

❌ Don’t use them as meal replacements.

✅ Stay organized with tools like the PROMIXX Core pill organizer.

✅ Respect dosages and listen to your body.

When you combine supplements with a balanced diet and healthy habits, they can be a powerful addition to your wellness routine. Think of them not as a magic fix, but as one more tool in your toolkit for living well.

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Written by Matthew Stogdon

Matt is a seasoned writer with 20 years of experience, leveraging understanding of fitness as a former rugby player and his insight from covering contact sports.