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MAY 24, 2024

The Best Vitamins to Counter Stress: A Comprehensive Guide

Take an in-depth look at the various vitamins, supplements, and other methods that can be utilized to reduce stress.

Read time: 12 minutes

Stress, we all get it, we all experience it. And if you’re thinking “Well, I don’t” you’re either incredibly blessed or might be in denial about sitting on a powder keg. Regardless, it often seems like the world can get on top of us and make every day a battle.

Thankfully, there are ways to navigate around these feelings and, more specifically, vitamins and supplements that can help alleviate stress.

Understanding the Impact of Stress on Your Body

Stress is an inevitable part of life, but when it becomes chronic, it can wreak havoc on your body. From headaches and fatigue to more serious conditions like hypertension and heart disease, the effects of prolonged stress are far-reaching. This is because stress triggers the release of cortisol - a hormone that can suppress your immune system, increase blood pressure, and contribute to weight gain. All of which contributes to more stress, in a vicious cycle.

What’s more, when you're constantly stressed, you might notice changes in your mood, sleep patterns, and even your digestive health. In fact, anxiety, depression, insomnia, and gastrointestinal issues like IBS (Irritable Bowel Syndrome) are common stress-induced conditions.

How Vitamins and Supplements Can Help Combat Stress

One effective way to combat stress is through proper nutrition. And vitamins and supplements can play a significant role in supporting your body's stress response. Here’s how:

Regulating Your Nervous System

Certain vitamins and minerals help balance neurotransmitters, which can improve mood and reduce anxiety.

Supporting Your Immune System

Chronic stress can weaken the immune system, making you more susceptible to illness. Vitamins can help bolster your immune defenses.

Reducing Inflammation

Some vitamins have anti-inflammatory properties that can counteract the inflammation caused by stress.

Key Vitamins and Supplements to Combat Stress

Vitamin B Complex

Vitamin B Complex is made up of 8 essential B vitamins, each playing a crucial role in maintaining optimal health, especially under stress.

  • B1 (Thiamine): Helps convert food into energy and is essential for nervous system function.
  • B2 (Riboflavin): Supports energy production and cellular function.
  • B3 (Niacin): Aids in DNA repair and stress-related hormone production.
  • B5 (Pantothenic Acid): Critical for the synthesis of coenzyme A, which is vital for metabolizing fats, proteins, and carbohydrates.
  • B6 (Pyridoxine): Involved in neurotransmitter synthesis, affecting mood regulation.
  • B7 (Biotin): Supports metabolism and overall health.
  • B9 (Folate): Essential for DNA synthesis and repair.
  • B12 (Cobalamin): Vital for red blood cell production and neurological function.

Foods Rich in Vitamin B Complex: Whole grains, eggs, dairy products, meat, fish, leafy green vegetables, and legumes.

Vitamin C

Vitamin C is a powerful antioxidant that helps reduce oxidative stress and supports the immune system. It also plays a role in the synthesis of cortisol, a stress hormone.

Foods Rich in Vitamin C: Citrus fruits (oranges, lemons, grapefruits), strawberries, bell peppers, broccoli, and Brussels sprouts.

Vitamin D

Vitamin D is crucial for bone health, immune function, and mood regulation. Low levels of Vitamin D have been linked to increased risks of depression and anxiety.

Foods Rich in Vitamin D: Fatty fish (salmon, mackerel), fortified dairy products, egg yolks, and sunlight exposure.

Omega-3 Fatty Acids

Omega-3 fatty acids, particularly EPA and DHA, are essential for brain health and reducing inflammation. They can help alleviate symptoms of depression and anxiety by supporting neurotransmitter function.

Foods Rich in Omega-3: Fatty fish (salmon, mackerel, sardines), flaxseeds, chia seeds, and walnuts.


Magnesium is a mineral that plays a key role in muscle relaxation and nervous system regulation. It can help reduce symptoms of anxiety and improve sleep quality.

Foods Rich in Magnesium: Dark leafy greens, nuts and seeds, whole grains, avocado, and dark chocolate.

3 Recommended Brands for Stress-Relief Supplements

MegaFood Balanced B Complex

MegaFood’s formula contains all 8 types of B vitamins, helping convert food into usable cellular energy. It also supports cognitive and nervous system health, thanks to Vitamins B6, B1, and B12. What’s more, it aids in red blood cell formation and neurotransmitter production for mood health with B6, B12, and Folate - all delivered with nourishing real foods.

Innate Vitality Magnesium Glycinate

Innate Vitality’s Magnesium Glycinate helps maintain a regular heartbeat and supports overall cardiovascular health. It promotes restful sleep, relieves muscle aches and cramps, and supports bone, heart, and nerve health.

HUM Nutrition Big Chill

Going out of their way to put the benefit right on the bottle, we have HUM Nutrition’s Big Chill. This formula helps balance adrenals, improves the body and mind’s response to stress and recovery from burnout, and enhances the ability to stay calm and focused. It uses 3% Rosavins and 1% Salidroside, clinically shown to reduce stress reactions and boost mental stamina.

Store your Vitamins and Supplements with PROMiXX CORE for Reduced Stress

We designed the PROMiXX CORE as an ideal solution for anyone looking to keep their daily supplements organized. Here’s how it works:

Handy Size

CORE is compact, making it easy to carry with you wherever you go. Whether you’re traveling, heading to work, or simply going about your day, you can have your supplements on hand.

Sleek, Comfortable Design

Its modern design is not only aesthetically pleasing but also comfortable to hold and use.

Magnetic Stackability

The magnetic feature allows you to stack multiple containers. You can keep them neatly organized on your fridge or any other magnetic surface, ensuring your pills are always in sight and easy to access.


The dividers within CORE help keep different supplements separate, preventing them from mixing together and ensuring you take the correct dose of each one.

Using a case like CORE can simplify your supplement routine, ensuring you never miss a dose and can consistently support your body in managing stress.

Other Ways to Mitigate Stress

While vitamins and supplements are greatly beneficial, they work best when combined with other stress-reducing practices. So let’s talk about a few additional methods to consider.


Meditation helps calm the mind, reduce anxiety, and improve overall emotional health. Regular practice can lower cortisol levels and enhance your ability to manage stress.


Yoga combines physical postures, breathing exercises, and meditation to promote relaxation and reduce stress. It improves flexibility, strength, and mental clarity.

Benefits of a Stress-Free or Stress-Reduced Life

It goes without saying that living with less stress has profound benefits for your physical and mental health. And if you didn’t believe that, you wouldn’t have read this far. But here are a few prime benefits:

  1. Improved Mood: Reduced stress levels can lead to a more positive outlook on life.
  2. Better Sleep: Lower stress often results in better sleep quality, which is essential for overall health.
  3. Enhanced Immune Function: Less stress means a stronger immune system, making you less prone to illnesses.
  4. Lower Risk of Chronic Diseases: Managing stress can reduce the risk of developing conditions like heart disease, hypertension, and diabetes.
  5. Increased Productivity: With less stress, you can focus better and be more productive in your daily activities.

So, in conclusion, while stress is an inevitable part of life, managing it effectively through a combination of vitamins, supplements, and lifestyle practices can greatly improve your quality of life. And by incorporating the strategies listed above, you can take a calm step toward a stress-free (or at the very least a stress-reduced) existence.

FAQs About Vitamins and Stress Management

Q: How quickly can I expect to see results from taking vitamins for stress relief?

A: The timeline for seeing results can vary depending on the individual and the specific vitamin or supplement. Generally, it might take a few weeks of consistent use to notice significant changes. For some people, improvements in mood and energy levels might be observed within a few days. It’s important to be patient and consistent with your supplement regimen.

Q: Can I get enough stress-relief vitamins from food alone?

A: While it's possible to get many essential vitamins from a balanced diet, stress can increase your body's nutrient needs. Supplements can help ensure you’re getting adequate amounts of key nutrients, especially if your diet isn't always perfect. Combining a nutrient-rich diet with supplements can provide optimal support for stress management.

Q: Are there any side effects of taking these vitamins and supplements?

A: Most people can take vitamins and supplements without any issues, but some may experience mild side effects such as digestive discomfort. It's important to follow the recommended dosages and consult with a healthcare professional, especially if you have any underlying health conditions or are taking other medications.

Q: Can I take all these supplements together?

A: Generally, yes, but it’s important to check for any potential interactions between supplements and medications you might be taking. It’s always a good idea to consult with a healthcare professional before starting a new supplement regimen to ensure it’s safe and effective for your specific needs.

Q: What is the best time of day to take these vitamins and supplements?

A: The best time can vary depending on the specific vitamin or supplement. For example:

  • B vitamins are best taken in the morning as they can boost energy levels.
  • Magnesium is often recommended in the evening because of its relaxing effects.
  • Vitamin D can be taken with meals to enhance absorption.
  • Omega-3 fatty acids can be taken with meals to reduce the risk of digestive upset.

Following the instructions on the supplement packaging or consulting with a healthcare professional can help you determine the optimal timing.

Q: How can I ensure I remember to take my supplements daily?

A: Using a pill holder like the PROMiXX CORE can be extremely helpful. Its handy size, magnetic stackability, and dividers for different supplements make it easy to keep your vitamins organized and in sight. Setting daily reminders on your phone can also help establish a routine.

Q: Are there any lifestyle changes that can enhance the effects of these vitamins on stress?

A: Absolutely! Combining supplements with healthy lifestyle practices can greatly enhance their effects. Consider incorporating:

  • Regular exercise: Physical activity can reduce stress hormones and boost mood.
  • Healthy diet: Eating a balanced diet rich in whole foods supports overall health and stress resilience.
  • Adequate sleep: Good sleep hygiene can improve your stress response.
  • Mindfulness practices: Techniques like meditation and yoga can help manage stress levels effectively.

Q: What should I do if I don’t notice any improvement in my stress levels after taking these supplements?

A: If you don't notice any improvement after a few weeks, consider consulting a healthcare professional. They can evaluate your overall health, check for any underlying issues, and potentially adjust your supplement regimen. It might also be helpful to review other aspects of your lifestyle, such as diet, exercise, and sleep habits, to ensure you’re addressing all potential contributors to stress.

Q: Can children and teenagers take these vitamins and supplements for stress?

A: Always a tricky one. It’s important to consult with a pediatrician before giving children or teenagers any supplements. Their nutritional needs and safe dosages can differ significantly from those of adults. A healthcare professional can provide guidance based on the individual’s specific health needs and age.

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Written by Matthew Stogdon

Matt has been writing for two decades, across print and digital media. He is also an accomplished filmmaker, with several accolades under his belt.


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